The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489
نویسندگان
چکیده
منابع مشابه
The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489.
RATIONALE Sustained cardiac hypertrophy is often accompanied by maladaptive cardiac remodeling leading to decreased compliance and increased risk for heart failure. Maladaptive hypertrophy is considered to be a therapeutic target for heart failure. MicroRNAs (miRNAs) and long noncoding RNAs (lncRNAs) have various biological functions and have been extensively investigated in past years. OBJEC...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.302476